Description

4-[3,5-Bis(Trifluoromethyl)Phenyl]Iodobenzene is a high-value, multi-fluorinated aromatic building block essential for advanced organic synthesis. This compound is prized for its ability to introduce both iodine and electron-deficient trifluoromethylphenyl groups into target molecules, enabling the creation of complex, functionalized structures. It is a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, particularly for developing active ingredients and specialty polymers.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the trifluoromethyl groups enhance biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for sophisticated ligands in transition metal catalysis, including cross-coupling reactions like Suzuki-Miyaura and Buchwald-Hartwig amination.
• Functional Material Precursor: Integral to the synthesis of organic semiconductors, liquid crystals, and other advanced materials requiring specific electronic and steric properties.
• Cross-Coupling Reactions: The iodine moiety makes it an excellent substrate for palladium-catalyzed cross-coupling reactions to form biaryl and other conjugated systems.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name	4-[3,5-Bis(Trifluoromethyl)Phenyl]Iodobenzene
CAS No.	886762-46-5
Molecular Formula	C14H6F6I
Molecular Weight	430.09 g/mol
Synonyms	1-Iodo-4-[3,5-bis(trifluoromethyl)phenyl]benzene; 4'-[3,5-Bis(trifluoromethyl)phenyl]iodobenzene; [3,5-Bis(trifluoromethyl)phenyl]-4-iodobenzene; 4-(3,5-Bis(trifluoromethyl)phenyl)iodobenzene; 4-Iodo-3',5'-bis(trifluoromethyl)biphenyl; 4-Iodophenyl-3,5-bis(trifluoromethyl)benzene
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards and precise customer requirements. Every batch is analyzed using advanced techniques including HPLC, GC, NMR, and mass spectrometry to verify identity, purity, and impurity profiles. Certificates of Analysis (COA) are available upon request, providing full transparency and traceability for your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is between 2°C and 8°C for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.