Description

4-Bromo-2-Fluorobenzylphthalimide is a high-purity, advanced pharmaceutical intermediate characterized by its unique halogenated benzylphthalimide structure. This compound matters for its critical role as a versatile building block in the synthesis of complex active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific bromo-fluoro substitution patterns into target molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, leveraging the halogenated aromatic system for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functionalized monomers for high-performance polymers and liquid crystals.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom chemical synthesis services targeting complex, multi-step organic transformations.
• Academic & Industrial R&D: Utilized in research laboratories for methodological studies in cross-coupling reactions and heterocyclic chemistry.

Basic Information

Product Name	4-Bromo-2-Fluorobenzylphthalimide
CAS No.	886761-90-6
Molecular Formula	C15H9BrFNO2
Molecular Weight	334.14 g/mol
Synonyms	4-Bromo-2-fluorobenzylphthalimide; 2-(4-Bromo-2-fluorobenzyl)isoindoline-1,3-dione; 1,3-Isoindolinedione, 2-[(4-bromo-2-fluorophenyl)methyl]-; 4-Bromo-2-fluoro-benzyl-phthalimide; 2-(4-Bromo-2-fluorobenzyl)-1H-isoindole-1,3(2H)-dione; 886761-90-6; 4-Bromo-2-fluorobenzyl phthalimide
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Fluorobenzylphthalimide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.