Description

Methyl 2-Amino-5-{[(2,3-Dichlorophenyl)Amino]-Carbonyl}-4-Methylthiophene-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its specific thiophene and dichlorophenylaniline structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) and novel chemical entities, offering a key building block for medicinal chemistry research and development. It is primarily utilized by pharmaceutical R&D laboratories, agrochemical manufacturers, and fine chemical producers engaged in the development of new therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and production of novel drug candidates, particularly those targeting specific receptor sites.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its heterocyclic core for biological activity.
• Medicinal Chemistry Research: Serves as a crucial scaffold for structure-activity relationship (SAR) studies and the discovery of new pharmacophores.
• Fine Chemical Production: Employed in the synthesis of complex, high-value specialty chemicals for various industrial applications.
• Contract Research & Manufacturing (CRAM): Supplied to organizations offering custom synthesis and process development services.
• Academic Research: Used in university and institutional labs for chemical research and the development of new synthetic methodologies.

Basic Information

Product Name	Methyl 2-Amino-5-{[(2,3-Dichlorophenyl)Amino]-Carbonyl}-4-Methylthiophene-3-Carboxylate
CAS No.	886657-53-0
Molecular Formula	C15H14Cl2N2O3S
Molecular Weight	373.25 g/mol
Synonyms	Methyl 2-amino-5-[(2,3-dichlorophenyl)carbamoyl]-4-methylthiophene-3-carboxylate; 2-Amino-5-[(2,3-dichlorophenyl)carbamoyl]-4-methylthiophene-3-carboxylic acid methyl ester; 886657-53-0; Thiophene-3-carboxylic acid, 2-amino-5-[[(2,3-dichlorophenyl)amino]carbonyl]-4-methyl-, methyl ester; Methyl 2-amino-4-methyl-5-[(2,3-dichlorophenyl)carbamoyl]thiophene-3-carboxylate
EINECS	Contact for details

Quality Control

Our Methyl 2-Amino-5-{[(2,3-Dichlorophenyl)Amino]-Carbonyl}-4-Methylthiophene-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP standards where applicable, ensuring reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). Keep away from incompatible materials such as strong acids and strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.