Description

n-1H-Indazol-5-Yl-Cyclobutanecarboxamide is a high-purity organic compound, specifically a cyclobutane carboxamide derivative, identified by CAS NO 886625-06-5. This compound is a critical building block in modern pharmaceutical research and development, valued for its unique molecular scaffold that enables the synthesis of novel bioactive molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for the development of kinase inhibitors and other targeted therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel drug candidates, especially in oncology and inflammatory disease research.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Kinase Inhibitor Synthesis: Serves as a vital building block for constructing potent and selective kinase inhibitors due to its indazole-cyclobutane motif.
• Biochemical Probe Development: Employed in the creation of chemical probes to study specific biological pathways and protein functions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of advanced intermediates under cGMP conditions.
• Academic Research: Utilized in university and institutional labs for exploratory synthetic chemistry and pharmacological studies.

Basic Information

Product Name	n-1H-Indazol-5-Yl-Cyclobutanecarboxamide
CAS No.	886625-06-5
Molecular Formula	C₁₂H₁₃N₃O
Molecular Weight	215.25 g/mol
Synonyms	5-(Cyclobutanecarboxamido)-1H-indazole; N-(1H-Indazol-5-yl)cyclobutanecarboxamide; Cyclobutanecarboxamide, N-(1H-indazol-5-yl)-; 1H-Indazole-5-carboxamide, N-cyclobutyl-; UNII-9Q8FQ8P4C3; 886625-06-5; AKOS025310647; BDBM50389303
EINECS	Contact for details

Quality Control

Our n-1H-Indazol-5-Yl-Cyclobutanecarboxamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and rigorous control of residual solvents and impurities. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or development specifications. Custom purity grades, including research (>95%), premium (>98%), and cGMP grades, are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (IR)	Spectrum matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.