Description

1-(Benzenesulfonyl)-1H-Pyrrolo[2,3-B]Pyridine-3-Boronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative, a critical building block in modern synthetic organic chemistry. Its value lies in its stability and reactivity, serving as a key intermediate in the construction of complex heterocyclic molecules via cross-coupling reactions. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries engaged in drug discovery and the development of novel active ingredients.

Application

This versatile boronic ester is primarily employed as a sophisticated synthetic intermediate. Its applications include:

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly those containing fused pyrrolopyridine scaffolds.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and insecticides with complex molecular architectures.
• Material Science: Serves as a building block for creating organic electronic materials and functional polymers.
• Chemical Biology: Utilized in the synthesis of molecular probes and tool compounds for biological target identification and validation.
• Catalyst Ligand Synthesis: Acts as a precursor for creating novel ligands used in asymmetric catalysis.
• Custom Synthesis & Contract Manufacturing: A critical raw material for fine chemical manufacturers producing bespoke compounds for client R&D programs.

Basic Information

Product Name	1-(Benzenesulfonyl)-1H-Pyrrolo[2,3-B]Pyridine-3-Boronic Acid Pinacol Ester
CAS No.	886547-94-0
Molecular Formula	C19H21BN2O4S
Molecular Weight	384.26 g/mol
Synonyms	1-(Phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-3-boronic acid pinacol ester; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine-3-boronic acid, 1-(benzenesulfonyl)-, 1,1-dimethylethyl ester; Benzenesulfonyl pyrrolopyridine boronic ester; 1-Benzenesulfonyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-b]pyridine; N-Benzenesulfonyl-7-azaindole-3-boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 1-(Benzenesulfonyl)-1H-Pyrrolo[2,3-B]Pyridine-3-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The container should be kept tightly sealed in a dry inert atmosphere to protect the boronic ester functionality from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.