Description

5-(2-Dimethoxymethyl-Phenyl)-Thiophene-2-Carbaldehyde is a high-purity organic building block featuring a thiophene core substituted with a carbaldehyde group and a dimethoxymethylphenyl moiety. This compound is valued for its role as a versatile synthetic intermediate in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and materials science sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing specific receptor activity.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, or insecticides, leveraging its heterocyclic structure for bioactivity.
• Organic Electronic Materials: Serves as a building block for conjugated polymers or small molecules used in organic light-emitting diodes (OLEDs), organic photovoltaics (OPVs), or field-effect transistors (OFETs).
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis, including those used in asymmetric synthesis or cross-coupling reactions.
• Chemical Biology Probes: Utilized to create fluorescent tags or molecular probes for studying biological processes and target engagement.
• Academic & Process Chemistry: A valuable reagent for methodological studies, route scouting, and scaling up synthetic pathways in both academic and industrial settings.

Basic Information

Product Name	5-(2-Dimethoxymethyl-Phenyl)-Thiophene-2-Carbaldehyde
CAS No.	886509-12-2
Molecular Formula	C15H16O3S
Molecular Weight	276.35 g/mol
Synonyms	5-(2-(Dimethoxymethyl)phenyl)thiophene-2-carboxaldehyde; 2-Thiophenecarboxaldehyde, 5-[2-(dimethoxymethyl)phenyl]-; 5-[2-(Dimethoxymethyl)phenyl]thiophene-2-carbaldehyde; α,α-Dimethoxy-o-tolualdehyde thiophene derivative; (5-Formylthiophen-2-yl)(2-(dimethoxymethyl)phenyl)methanone precursor; CAS 886509-12-2
EINECS	Contact for details

Quality Control

Our production of 5-(2-Dimethoxymethyl-Phenyl)-Thiophene-2-Carbaldehyde adheres to stringent internal quality protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support cGMP-compliant manufacturing for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.