Description

5-(2-Bromo-Phenyl)-Thiophene-2-Carbaldehyde is a versatile brominated aromatic aldehyde building block with significant synthetic utility. This compound is valued for its role as a key intermediate in the synthesis of complex organic molecules, particularly in pharmaceutical and materials science research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing novel heterocyclic frameworks.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing thiophene and biphenyl motifs for therapeutic agents.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Material Science Research: Serves as a building block for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its conjugated thiophene-aldehyde system.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions, a cornerstone of modern synthetic chemistry.
• Chemical Biology Probes: Utilized as a scaffold for developing fluorescent tags or molecular probes to study biological processes.
• Academic & Industrial R&D: A fundamental reagent for methodological development in organic synthesis, including Suzuki-Miyaura and other palladium-catalyzed couplings.

Basic Information

Product Name	5-(2-Bromo-Phenyl)-Thiophene-2-Carbaldehyde
CAS No.	886509-00-8
Molecular Formula	C11H7BrOS
Molecular Weight	267.14 g/mol
Synonyms	2-Bromo-5-thiophenecarboxaldehyde benzene; 5-(2-Bromophenyl)thiophene-2-carboxaldehyde; 2-(2-Bromophenyl)thiophene-5-carbaldehyde; (5-(2-Bromophenyl)thiophen-2-yl)methanal; 886509-00-8; Thiophene-2-carbaldehyde, 5-(2-bromophenyl)-; 5-(o-Bromophenyl)thiophene-2-carbaldehyde
EINECS	Contact for details

Quality Control

Our 5-(2-Bromo-Phenyl)-Thiophene-2-Carbaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.