Description

5-(1-Hydroxy-Cyclohexylethynyl)-Thiophene-2-Carboxylic Acid is a specialized organic building block featuring a thiophene core functionalized with a hydroxy-cyclohexyl-ethynyl group. This compound is valued for its unique molecular architecture, which makes it a versatile intermediate in advanced synthetic chemistry. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders or metabolic diseases.
• Agrochemical Research: Used in the synthesis of novel pesticides and herbicides, leveraging the thiophene moiety for bioactivity.
• Material Science Precursor: Serves as a building block for organic electronic materials, such as conductive polymers or semiconductors, due to the conjugated thiophene system.
• Chemical Synthesis: Employed in academic and industrial R&D for complex molecule construction, including natural product synthesis and catalyst development.
• Ligand and Catalyst Design: The carboxylic acid and alkyne functionalities make it suitable for creating chelating ligands or organometallic catalysts.

Basic Information

Product Name	5-(1-Hydroxy-Cyclohexylethynyl)-Thiophene-2-Carboxylic Acid
CAS No.	886505-55-1
Molecular Formula	C13H14O3S
Molecular Weight	250.31 g/mol
Synonyms	5-[(1-Hydroxycyclohexyl)ethynyl]thiophene-2-carboxylic acid; 5-(1-Hydroxy-cyclohexylethynyl)-thiophene-2-carboxylic acid; 2-Thiophenecarboxylic acid, 5-[(1-hydroxycyclohexyl)ethynyl]-; 886505-55-1; Thiophene-2-carboxylic acid, 5-(1-hydroxycyclohexylethynyl)-
EINECS	Contact for details

Quality Control

Our 5-(1-Hydroxy-Cyclohexylethynyl)-Thiophene-2-Carboxylic Acid is manufactured under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.