Description

5-Methyl-2-(Trifluoromethyl)Benzyl Alcohol is a versatile fluorinated aromatic alcohol building block of significant interest in advanced organic synthesis. Its core value lies in the unique combination of the benzyl alcohol functionality and the electron-withdrawing trifluoromethyl group, which imparts desirable properties to final compounds. This intermediate is primarily needed by pharmaceutical, agrochemical, and material science R&D teams for the development of novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the CF3 group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated aromatic cores in advanced electronic materials, contributing to improved performance in displays and lighting.
• Polymer Modification: Incorporated into polymer chains to modify thermal stability, chemical resistance, and surface properties of high-performance engineering plastics and coatings.
• Ligand & Catalyst Development: Utilized in organometallic chemistry for the synthesis of specialized ligands that can modulate catalyst activity and selectivity in asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up production under cGMP or ISO standards for client-specific molecules.

Basic Information

Product Name	5-Methyl-2-(Trifluoromethyl)Benzyl Alcohol
CAS No.	886502-81-4
Molecular Formula	C9H9F3O
Molecular Weight	190.16 g/mol
Synonyms	α,α,α-Trifluoro-2,5-dimethylbenzyl Alcohol; (5-Methyl-2-(trifluoromethyl)phenyl)methanol; 2-(Trifluoromethyl)-5-methylbenzyl Alcohol; 2,5-Dimethyl-α,α,α-trifluorobenzyl Alcohol; 1-(5-Methyl-2-(trifluoromethyl)phenyl)methanol; 5-Methyl-α,α,α-trifluoro-o-tolylmethanol
EINECS	Contact for details

Quality Control

Our 5-Methyl-2-(Trifluoromethyl)Benzyl Alcohol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0% (Standard Grade)
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.