Description

2,6-Difluoro-3-Methoxybenzyl Alcohol is a high-purity fluorinated benzyl alcohol derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of fluorine and methoxy substituents, which are essential for modulating the biological activity, metabolic stability, and physicochemical properties of target molecules. This intermediate is primarily needed by pharmaceutical R&D and agrochemical manufacturers for the development of novel active ingredients, including kinase inhibitors and other small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of complex drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where fluorine atoms enhance efficacy and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor for fluorinated compounds used in electronic display technologies.
• Organic Light-Emitting Diodes (OLEDs): Acts as a building block for electron-transport or host materials in OLED fabrication.
• Chemical Research & Development: Employed in academic and industrial labs for exploring new fluorination methodologies and structure-activity relationships.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds under cGMP or research-grade conditions.

Basic Information

Product Name	2,6-Difluoro-3-Methoxybenzyl Alcohol
CAS No.	886498-45-9
Molecular Formula	C9H9F2O2
Molecular Weight	187.16 g/mol
Synonyms	2,6-Difluoro-3-methoxybenzenemethanol; (2,6-Difluoro-3-methoxyphenyl)methanol; 3-Methoxy-2,6-difluorobenzyl alcohol; Benzenemethanol, 2,6-difluoro-3-methoxy-; 886498-45-9; 2,6-Difluoro-3-methoxybenzylalcohol; 2,6-Difluoro-m-anisyl alcohol
EINECS	Contact for details

Quality Control

Our 2,6-Difluoro-3-Methoxybenzyl Alcohol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Production can be aligned with cGMP guidelines for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere to minimize moisture uptake and potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.