Description

2,4,5-Trifluorobenzylmercaptan is a specialized fluorinated organosulfur building block of significant interest in advanced chemical synthesis. Its value lies in its unique trifluoromethylbenzyl thiol structure, which serves as a critical precursor for introducing specific fluorinated motifs into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, where the fluorine atoms improve metabolic stability and bioavailability.
• Liquid Crystal Materials: Serves as a precursor for fluorinated components in electronic display technologies.
• Functional Material Research: Employed in creating novel polymers and ligands with tailored electronic and surface properties.
• Cross-Coupling Reactions: Acts as a versatile thiol reagent in palladium-catalyzed and other metal-mediated coupling reactions.
• Chemical Biology Probes: Useful for bioconjugation and labeling applications due to the reactive thiol group.

Basic Information

Product Name	2,4,5-Trifluorobenzylmercaptan
CAS No.	886498-39-1
Molecular Formula	C7H5F3S
Molecular Weight	178.18 g/mol
Synonyms	(2,4,5-Trifluorophenyl)methanethiol; α,2,4-Trifluoro-benzenemethanethiol; 2,4,5-Trifluorobenzyl Thiol; 2,4,5-Trifluoro-α-toluenethiol; 1-(Mercaptomethyl)-2,4,5-trifluorobenzene; Benzenemethanethiol, 2,4,5-trifluoro-; 886498-39-1 (CAS)
EINECS	Contact for details

Quality Control

Our 2,4,5-Trifluorobenzylmercaptan is produced under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its highly volatile and light-sensitive nature, minimize exposure to air and light during handling. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.