Description

4-Bromo-2-Fluorobenzyl Mercaptan is a high-purity organosulfur building block characterized by its reactive thiol (-SH) and halogenated benzyl structure. This compound matters for its versatility as a key intermediate in advanced organic synthesis, enabling the introduction of sulfur-containing functional groups into complex molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as drug discovery, ligand synthesis, and the development of novel crop protection agents.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, leveraging its halogen and sulfur motifs.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and advanced organic materials.
• Custom Chemical Synthesis: A versatile reagent for contract research organizations (CROs) and CDMOs performing bespoke synthesis for clients.
• Bioconjugation Chemistry: The thiol group allows for site-specific modification of proteins, peptides, and other biomolecules in biotech research.

Basic Information

Product Name	4-Bromo-2-Fluorobenzyl Mercaptan
CAS No.	886498-29-9
Molecular Formula	C7H6BrFS
Molecular Weight	221.09 g/mol
Synonyms	2-Fluoro-4-bromobenzyl mercaptan; (4-Bromo-2-fluorophenyl)methanethiol; 1-Bromo-4-[(mercaptomethyl)-3-fluorobenzene; 4-Bromo-2-fluoro-α-toluenethiol; α-Mercapto-4-bromo-2-fluorotoluene; 4-Bromo-2-fluorobenzylthiol; 886498-29-9
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Fluorobenzyl Mercaptan is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring traceability and consistency for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and degradation of the thiol group. Keep the container in a cool, dry, and well-ventilated place, away from heat, sparks, and open flames. Separate from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.