Description

Ethyl 2-(sec-Butylamino)-4-(Trifluoromethyl)-1,3-Thiazole-5-Carboxylate is a high-value, functionalized thiazole derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring a trifluoromethyl group and a secondary butylamino substituent, makes it a versatile building block for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, or infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the trifluoromethyl group can enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or functional additive in the research of specialty polymers and advanced materials with specific electronic or surface properties.
• Chemical Synthesis Reagent: Employed in academic and industrial R&D for constructing complex heterocyclic frameworks and introducing the pharmacologically privileged thiazole motif.
• Ligand and Catalyst Development: Utilized in the preparation of novel ligands for metal catalysis or as a scaffold for organocatalysts in asymmetric synthesis.

Basic Information

Product Name	Ethyl 2-(sec-Butylamino)-4-(Trifluoromethyl)-1,3-Thiazole-5-Carboxylate
CAS No.	886498-27-7
Molecular Formula	C11H15F3N2O2S
Molecular Weight	296.31 g/mol
Synonyms	Ethyl 2-[(butan-2-yl)amino]-4-(trifluoromethyl)-1,3-thiazole-5-carboxylate; 2-(sec-Butylamino)-4-(trifluoromethyl)thiazole-5-carboxylic acid ethyl ester; 5-Carbethoxy-2-(sec-butylamino)-4-(trifluoromethyl)thiazole; Ethyl 2-(N-sec-butylamino)-4-trifluoromethylthiazole-5-carboxylate; 886498-27-7; 4-(Trifluoromethyl)-2-[(1-methylpropyl)amino]-5-thiazolecarboxylic acid ethyl ester; Ethyl α-[(1-methylpropyl)amino]-4-(trifluoromethyl)-5-thiazoleacetate (tautomeric form)
EINECS	Contact for details

Quality Control

Our production of Ethyl 2-(sec-Butylamino)-4-(Trifluoromethyl)-1,3-Thiazole-5-Carboxylate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5% w/w
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.