Description

Boc-3-Amino-Thiophene-2-Carboxamide is a high-purity, protected heterocyclic building block essential for advanced organic synthesis. This compound is valued for its role as a versatile intermediate in the development of novel pharmaceuticals and agrochemicals. It is primarily sought by research institutions and industrial manufacturers engaged in medicinal chemistry, particularly for the synthesis of thiophene-based drug candidates and complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), especially those containing the thiophene pharmacophore.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and combinatorial chemistry for lead optimization and library synthesis.
• Agrochemical Research: Serves as a building block for creating novel herbicides, fungicides, and insecticides with potential enhanced efficacy.
• Peptide Mimetics: The carboxamide and protected amino groups make it suitable for constructing peptide analogs and bioisosteres.
• Material Science: Potential precursor for specialty polymers or organic electronic materials due to the thiophene core.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations offering custom synthesis and process development services.

Basic Information

Product Name	Boc-3-Amino-Thiophene-2-Carboxamide
CAS No.	886497-80-9
Molecular Formula	C10H14N2O3S
Molecular Weight	242.29 g/mol
Synonyms	tert-Butyl (3-amino-2-carbamoylthiophen-1-yl)carbamate; 1-[(tert-Butoxycarbonyl)amino]-3-amino-2-thiophenecarboxamide; 3-Amino-N-(tert-butoxycarbonyl)-2-thiophenecarboxamide; Boc-3-Amino-2-carbamoylthiophene; 2-Carbamoyl-3-aminothiophene-1-carboxylic acid tert-butyl ester; Boc-Amino-Thiophene-Carboxamide; 886497-80-9
EINECS	Contact for details

Quality Control

Our Boc-3-Amino-Thiophene-2-Carboxamide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of our global customer base in the fine chemical and pharmaceutical sectors.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.