Description

4-Chloro-2-(Trifluoromethyl)Benzyl Bromide is a versatile and highly functionalized organic intermediate, prized for its reactive benzyl bromide moiety and halogenated aromatic ring. This compound is critical for introducing the 4-chloro-2-(trifluoromethyl)benzyl group into target molecules, enabling the synthesis of advanced materials and active ingredients. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the trifluoromethyl and chloro groups enhance biological activity and environmental stability.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands for metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the creation of advanced polymers, liquid crystals, and organic electronic materials due to its unique electronic properties imparted by the halogen and fluorine atoms.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving diverse client projects.

Basic Information

Item	Details
Product Name	4-Chloro-2-(Trifluoromethyl)Benzyl Bromide
CAS No.	886496-75-9
Molecular Formula	C8H5BrClF3
Molecular Weight	273.48 g/mol
Synonyms	1-(Bromomethyl)-4-chloro-2-(trifluoromethyl)benzene; α-Bromo-4-chloro-α,α,α-trifluoro-o-xylene; (4-Chloro-2-(trifluoromethyl)phenyl)methyl bromide; 4-Chloro-α-(bromomethyl)-α,α,α-trifluoro-o-toluene; 2-(Trifluoromethyl)-4-chlorobenzyl bromide
EINECS	Contact for details

Quality Control

Every batch of 4-Chloro-2-(Trifluoromethyl)Benzyl Bromide is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets your specific research or production requirements. A detailed Certificate of Analysis (COA), including results for purity (HPLC/GC), identity (IR, NMR), and impurity profile, is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. Due to its light-sensitive nature and reactive bromide group, prolonged exposure to light or moisture should be avoided to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0% (Standard Grade)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.