Description

3-(4-Carboxy-Phenyl)-Indole-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate and versatile chemical building block. This compound is critical for the synthesis of complex organic molecules, particularly in medicinal chemistry and drug discovery programs. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in developing novel active pharmaceutical ingredients (APIs) and other specialty compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting specific receptor pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Organic Synthesis Reagent: Serves as a versatile precursor for constructing complex indole-based heterocyclic systems.
• API Development: Integral in the research and process development stages for new Active Pharmaceutical Ingredients (APIs).
• Bioconjugation & Probe Synthesis: Potential use in creating labeled compounds or probes for biochemical and diagnostic applications.
• Academic & Industrial R&D: Employed in chemical libraries and for exploring new synthetic methodologies in academic and industrial laboratories.

Basic Information

Item	Details
Product Name	3-(4-Carboxy-Phenyl)-Indole-1-Carboxylic Acid tert-Butyl Ester
CAS No.	886370-74-7
Molecular Formula	C20H19NO4
Molecular Weight	337.37 g/mol
Synonyms	tert-Butyl 3-(4-carboxyphenyl)-1H-indole-1-carboxylate; 1H-Indole-1-carboxylic acid, 3-[4-(carboxy)phenyl]-, 1,1-dimethylethyl ester; 3-(4-Carboxyphenyl)indole-1-carboxylic Acid tert-Butyl Ester; 3-(4-Carboxy-phenyl)-indole-1-carboxylic acid tert-butyl ester; BOC-Protected 3-(4-Carboxyphenyl)indole; 886370-74-7
EINECS	Contact for details

Quality Control

Our 3-(4-Carboxy-Phenyl)-Indole-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.