Description

3-Pyrrolidin-2-Ylmethyl-Indole-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate featuring a complex heterocyclic structure. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for the synthesis of novel bioactive molecules. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for the creation of potential drug candidates targeting central nervous system and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those with indole and pyrrolidine pharmacophores.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies for new therapeutic agents.
• Process Chemistry Development: Serves as a starting material or intermediate in scaling up synthetic routes under current Good Manufacturing Practice (cGMP) guidelines.
• Library Synthesis for Drug Discovery: Employed in the generation of diverse compound libraries for high-throughput screening against biological targets.
• Academic Research: Utilized in university and institutional labs for investigating novel synthetic methodologies and reaction mechanisms.
• Contract Research and Manufacturing (CRAM): Supplied to organizations offering custom synthesis and development services for the pharmaceutical industry.

Basic Information

Product Name	3-Pyrrolidin-2-Ylmethyl-Indole-1-Carboxylic Acid tert-Butyl Ester
CAS No.	886370-63-4
Molecular Formula	C19H26N2O2
Molecular Weight	314.43 g/mol
Synonyms	1H-Indole-1-carboxylic acid, 3-[(2-pyrrolidinyl)methyl]-, 1,1-dimethylethyl ester; tert-Butyl 3-(pyrrolidin-2-ylmethyl)-1H-indole-1-carboxylate; 3-(2-Pyrrolidinylmethyl)-1H-indole-1-carboxylic acid tert-butyl ester; 886370-63-4; BOC-protected 3-(pyrrolidin-2-ylmethyl)indole; 3-(Pyrrolidin-2-ylmethyl)indole-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our 3-Pyrrolidin-2-Ylmethyl-Indole-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all test results are provided and available upon request. We support development projects requiring material suitable for use under ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.