Description

3-Pyrrolidin-3-Yl-Indole-1-Carboxylic Acid tert-Butyl Ester is a high-value, advanced pharmaceutical intermediate featuring a unique indole-pyrrolidine hybrid scaffold. This compound is critical for medicinal chemistry research and development, enabling the synthesis of novel bioactive molecules. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents, particularly in the areas of central nervous system (CNS) and oncology drug discovery.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of complex drug candidates, especially those targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its versatile indole-pyrrolidine core.
• Protease Inhibitor Development: The structural motif is relevant for the design of inhibitors for various protease enzymes.
• Chemical Biology Probes: Employed in the creation of molecular probes to study biological processes and identify new drug targets.
• Custom Synthesis: A starting material for the contract manufacturing of specialized APIs (Active Pharmaceutical Ingredients) and reference standards.
• Academic Research: Used in university and institutional labs for exploratory synthetic chemistry and pharmacology projects.

Basic Information

Product Name	3-Pyrrolidin-3-Yl-Indole-1-Carboxylic Acid tert-Butyl Ester
CAS No.	886370-44-1
Molecular Formula	C17H22N2O2
Molecular Weight	286.37 g/mol
Synonyms	1H-Indole-1-carboxylic acid, 3-(3-pyrrolidinyl)-, 1,1-dimethylethyl ester; tert-Butyl 3-(pyrrolidin-3-yl)-1H-indole-1-carboxylate; 3-(3-Pyrrolidinyl)-1H-indole-1-carboxylic acid tert-butyl ester; 1-Boc-3-(3-pyrrolidinyl)indole; 3-(1H-Indol-3-yl)pyrrolidine-1-carboxylic acid tert-butyl ester (tautomer); 886370-44-1; Pyrrolidin-3-yl-indole tert-butyl ester
EINECS	Contact for details

Quality Control

Our 3-Pyrrolidin-3-Yl-Indole-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research and development. We adhere to cGMP principles where applicable. A comprehensive Certificate of Analysis (COA) is provided with each batch, detailing purity, identity, and impurity profiles. Our quality commitment ensures the material meets the stringent requirements of pharmaceutical and advanced synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive (store away from light). Keep container tightly sealed in a dry environment to minimize moisture exposure.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.