Description

2-(4-Fluoro-Phenyl)-Thiazole-5-Carboxylic Acid is a high-purity, versatile heterocyclic building block essential for advanced organic synthesis. This compound serves as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique thiazole core and carboxylic acid functionality enable precise molecular modifications. It is primarily sought after by research and development chemists, process development teams, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates, particularly those targeting neurological disorders, anti-inflammatory agents, and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiazole moiety.
• Material Science Research: Serves as a building block for creating novel organic ligands, polymers, and liquid crystals with specific electronic or optical properties.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in CDMO (Contract Development and Manufacturing Organization) facilities.

Basic Information

Product Name	2-(4-Fluoro-Phenyl)-Thiazole-5-Carboxylic Acid
CAS No.	886370-04-3
Molecular Formula	C10H6FNO2S
Molecular Weight	223.22 g/mol
Synonyms	5-Thiazolecarboxylic acid, 2-(4-fluorophenyl)-; 2-(4-Fluorophenyl)-1,3-thiazole-5-carboxylic acid; 2-(p-Fluorophenyl)thiazole-5-carboxylic acid; 4-Fluoro-2-(thiazol-5-yl)benzoic acid (tautomeric form); FPTA; 886370-04-3; 2-(4-Fluorophenyl)-5-carboxythiazole
EINECS	Contact for details

Quality Control

Our production of 2-(4-Fluoro-Phenyl)-Thiazole-5-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability. Each lot is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry to verify identity, purity, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support compliance with cGMP, ISO, and REACH standards for global supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.