Description

2-(3-Bromo-Phenyl)-Thiazole-4-Carboxylic Acid is a high-purity, versatile heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its bifunctional structure, featuring both a carboxylic acid group and a brominated aromatic system, which enables precise molecular construction for complex target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it serves as a key intermediate for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors, anti-inflammatory agents, and CNS-active compounds.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its thiazole core for bioactivity.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the synthesis of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probe: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways due to its modifiable functional groups.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-specific, multi-step synthetic routes.

Basic Information

Product Name	2-(3-Bromo-Phenyl)-Thiazole-4-Carboxylic Acid
CAS No.	886369-02-4
Molecular Formula	C10H6BrNO2S
Molecular Weight	284.13 g/mol
Synonyms	3-Bromo-2-phenyl-4-thiazolecarboxylic acid; 2-(3-Bromophenyl)-1,3-thiazole-4-carboxylic acid; 4-Thiazolecarboxylic acid, 2-(3-bromophenyl)-; 886369-02-4; 2-(3-Bromophenyl)thiazole-4-carboxylic acid; (3-Bromophenyl)thiazole-4-carboxylic acid; 2-(m-Bromophenyl)-4-thiazolecarboxylic acid
EINECS	Contact for details

Quality Control

We maintain a rigorous quality management system to ensure batch-to-batch consistency and high purity. Our standard offering for this intermediate typically meets a purity specification of ≥95% (by HPLC), with options for higher grades (≥98% and ≥99%) available. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity (IR, NMR), purity (HPLC), and relevant impurity profiles. Our production adheres to cGMP principles where applicable, ensuring traceability and documentation for regulated applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.