Description

5-Fluoro-1-Methyl-1H-Indazole-3-Carboxylic Acid is a high-purity, synthetically versatile indazole derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its functionalized structure, which allows for precise chemical modifications to create novel compounds with targeted properties. This intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially in oncology, neurology, and anti-inflammatory research.
• Agrochemical Development: Used in the research and production of advanced pesticides and herbicides due to its bioactive indazole core.
• Organic Synthesis Building Block: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Material Science Research: Investigated as a monomer or functional component in the development of specialty polymers and advanced materials.
• Academic & Contract Research: Serves as a standard or starting material in university laboratories and CROs (Contract Research Organizations) for method development and discovery chemistry.

Basic Information

Product Name	5-Fluoro-1-Methyl-1H-Indazole-3-Carboxylic Acid
CAS No.	886368-88-3
Molecular Formula	C9H7FN2O2
Molecular Weight	194.16 g/mol
Synonyms	5-Fluoro-1-methyl-1H-indazole-3-carboxylic acid; 1-Methyl-5-fluoroindazole-3-carboxylic acid; 5-Fluoro-1-methylindazole-3-carboxylic acid; 886368-88-3; 3-Carboxy-5-fluoro-1-methylindazole; 5-Fluoro-1-methyl-3-indazolecarboxylic acid; 1-Methyl-5-fluoro-1H-indazole-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 5-Fluoro-1-Methyl-1H-Indazole-3-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for your critical synthesis workflows. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.