Description

7-Fluoro-2,3,4,5-Tetrahydro-1H-Benzo[B]Azepin-5-Ylamine is a high-purity, advanced pharmaceutical intermediate belonging to the benzazepine class of heterocyclic compounds. Its core value lies in its role as a critical building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and psychiatric drug discovery. This compound is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical and biotechnology industries seeking to develop new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel benzazepine-based drug candidates targeting neurological disorders.
• Drug Discovery & Medicinal Chemistry: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in R&D laboratories.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the final or penultimate stages of manufacturing complex APIs for potential therapeutic use.
• Biochemical Research: Employed as a standard or reference compound in pharmacological assays and receptor binding studies.
• Contract Manufacturing (CMO): Supplied to contract development and manufacturing organizations (CDMOs) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for the study of heterocyclic chemistry and new synthetic methodologies.

Basic Information

Product Name	7-Fluoro-2,3,4,5-Tetrahydro-1H-Benzo[B]Azepin-5-Ylamine
CAS No.	886367-50-6
Molecular Formula	C10H13FN2
Molecular Weight	180.22 g/mol
Synonyms	5-Amino-7-fluoro-2,3,4,5-tetrahydro-1H-1-benzazepine; 7-Fluoro-1,2,3,4-tetrahydro-5H-1-benzazepin-5-amine; 5-Amino-7-fluoro-1,2,3,4-tetrahydro-5H-1-benzazepine; 7-Fluoro-2,3,4,5-tetrahydro-1H-1-benzazepin-5-amine; 886367-50-6; 7-Fluoro-5-amino-2,3,4,5-tetrahydro-1H-benzo[b]azepine
EINECS	Contact for details

Quality Control

Our 7-Fluoro-2,3,4,5-Tetrahydro-1H-Benzo[B]Azepin-5-Ylamine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical R&D. All products undergo rigorous analytical testing, including HPLC, GC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.