Description

Ethyl 4-(4-Fluorophenyl)-2-thiazolecarboxylate is a high-value fluorinated heterocyclic building block essential for advanced organic synthesis. This compound is critical for researchers and manufacturers developing novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique thiazole core and fluorinated aromatic ring enable precise molecular design. It is primarily utilized by the pharmaceutical, agrochemical, and specialty chemical industries for the research and development of new therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antimicrobials.
• Agrochemical Research: Serves as a crucial building block for developing new-generation herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science Precursor: Used in the research of advanced organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its electron-deficient thiazole moiety.
• Chemical Biology Probe: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and as a scaffold for designing enzyme inhibitors.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and non-commercial research quantities.

Basic Information

Item	Detail
Product Name	Ethyl 4-(4-Fluorophenyl)-2-thiazolecarboxylate
CAS No.	886366-37-6
Molecular Formula	C12H10FNO2S
Molecular Weight	251.28 g/mol
Synonyms	Ethyl 4-(4-fluorophenyl)thiazole-2-carboxylate; 2-Thiazolecarboxylic acid, 4-(4-fluorophenyl)-, ethyl ester; 4-(4-Fluorophenyl)-2-thiazolecarboxylic acid ethyl ester; Ethyl 4-(p-fluorophenyl)-2-thiazolecarboxylate; 886366-37-6; AKOS006361889; FT-0775787; EN300-131077; Ethyl 4-(4-fluorophenyl)-1,3-thiazole-2-carboxylate
EINECS	Contact for details

Quality Control

Our production of Ethyl 4-(4-Fluorophenyl)-2-thiazolecarboxylate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, GC-MS, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be stored away from light as indicated.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Any single unknown impurity	≤0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.