Description

[1-(2-Chloro-Phenyl)-Cyclopropyl]-Methanol is a high-purity, functionalized cyclopropane derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and valuable chiral building block for constructing complex molecular architectures. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced pesticide and herbicide intermediates, leveraging the biological activity imparted by the chlorophenyl and cyclopropyl motifs.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to control stereochemistry.
• Material Science Research: Employed in the synthesis of specialty monomers and polymers with tailored properties for advanced materials.
• Chemical Biology Probes: Useful for constructing molecular probes to study enzyme function and biological pathways.
• Custom Synthesis and Scale-Up: Available for contract research organizations (CROs) and CDMOs requiring reliable, high-quality building blocks for custom synthesis projects from gram to kilogram scale.

Basic Information

Product Name	[1-(2-Chloro-Phenyl)-Cyclopropyl]-Methanol
CAS No.	886366-24-1
Molecular Formula	C10H11ClO
Molecular Weight	182.65 g/mol
Synonyms	(1-(2-Chlorophenyl)cyclopropyl)methanol; 1-(2-Chlorophenyl)cyclopropanemethanol; α-(2-Chlorophenyl)cyclopropanemethanol; (1-(2-Chloro-phenyl)-cyclopropyl)-methanol; 2-Chloro-α-(hydroxymethyl)benzenepropanenitrile (incorrect but common misnomer); 2-Chlorobenzenecyclopropanemethanol; (2-Chlorophenyl)cyclopropylcarbinol
EINECS	Contact for details

Quality Control

Every batch of [1-(2-Chloro-Phenyl)-Cyclopropyl]-Methanol is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent batch-to-batch performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under a dry atmosphere to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.