Description

2-(4-Benzylpiperidino)-1,3-Thiazole-5-Carbaldehyde is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure combining a thiazole and a benzylpiperidine moiety. This compound is of significant value in medicinal chemistry for its role as a versatile building block in the synthesis of novel bioactive molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within the fields of central nervous system (CNS) and oncology drug discovery.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of potential drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a core scaffold or derivatization point in structure-activity relationship (SAR) studies to optimize potency and selectivity.
• CNS Drug Development: Serves as a building block for compounds being investigated for neurological and psychiatric disorders, leveraging the benzylpiperidine pharmacophore.
• Oncology Research: Employed in the synthesis of molecules designed to inhibit specific enzymes or protein-protein interactions involved in cancer cell proliferation.
• Chemical Biology Probes: Utilized to create tool compounds for studying biological processes and target validation in cellular assays.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP or research-grade conditions.

Basic Information

Product Name	2-(4-Benzylpiperidino)-1,3-Thiazole-5-Carbaldehyde
CAS No.	886362-09-0
Molecular Formula	C16H18N2OS
Molecular Weight	286.40 g/mol
Synonyms	5-Formyl-2-(4-benzyl-1-piperidinyl)thiazole; 2-(4-Benzyl-1-piperidinyl)-1,3-thiazole-5-carboxaldehyde; 1,3-Thiazole-5-carboxaldehyde, 2-(4-benzyl-1-piperidinyl)-; 2-(4-Benzylpiperidin-1-yl)thiazole-5-carbaldehyde; 886362-09-0; Thiazole-5-carbaldehyde derivative
EINECS	Contact for details

Quality Control

Our 2-(4-Benzylpiperidino)-1,3-Thiazole-5-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). Keep container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.