Description

Ethyl 5-(3-Nitrophenyl)-2-thiophenecarboxylate is a high-purity, specialized organic building block of significant interest in advanced chemical synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and material science. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Research: Used in the development of new generation herbicides and fungicides, leveraging the thiophene and nitrophenyl motifs for bioactivity.
• Material Science: Acts as a monomer or building block for creating conjugated polymers and organic semiconductors for electronic applications.
• Chemical Synthesis: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) to introduce complex thiophene-based units into larger molecules.
• Dye & Pigment Industry: Functions as an intermediate for synthesizing specialized dyes and pigments with specific light-absorption properties.
• Academic & Contract Research: Essential for methodological studies in heterocyclic and medicinal chemistry within university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	Ethyl 5-(3-Nitrophenyl)-2-thiophenecarboxylate
CAS No.	886361-77-9
Molecular Formula	C13H11NO4S
Molecular Weight	277.30 g/mol
Synonyms	Ethyl 5-(3-nitrophenyl)thiophene-2-carboxylate; 2-Thiophenecarboxylic acid, 5-(3-nitrophenyl)-, ethyl ester; 5-(3-Nitrophenyl)thiophene-2-carboxylic acid ethyl ester; Ethyl 5-(m-nitrophenyl)thiophene-2-carboxylate; 886361-77-9; AKOS015903991; ZINC3848266
EINECS	Contact for details

Quality Control

Our Ethyl 5-(3-Nitrophenyl)-2-thiophenecarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.