Description

1-(5-(4-Fluorophenyl)Thiophen-2-Yl)Ethanone is a high-purity fluorinated thiophene derivative, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in its unique molecular architecture, which combines a fluorinated aromatic ring with a thiophene-acetyl moiety, making it an essential building block for creating complex molecules with tailored properties. This compound is primarily needed by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and materials science sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used as a precursor in the design and synthesis of next-generation pesticides and herbicides, leveraging the fluorine atom for enhanced bioactivity and environmental stability.
• Organic Electronic Materials: Serves as a building block for π-conjugated systems in the development of organic semiconductors, OLEDs (Organic Light-Emitting Diodes), and photovoltaic materials.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for catalysis and metal-organic frameworks (MOFs) due to its electron-rich thiophene core.
• Chemical Research: A versatile reagent for academic and industrial research in heterocyclic and fluorine chemistry, enabling structure-activity relationship (SAR) studies.
• Fine Chemical Production: An intermediate in the multi-step synthesis of complex fine chemicals and specialty dyes.

Basic Information

Product Name	1-(5-(4-Fluorophenyl)Thiophen-2-Yl)Ethanone
CAS No.	886361-46-2
Molecular Formula	C12H9FOS
Molecular Weight	220.26 g/mol
Synonyms	2-Acetyl-5-(4-fluorophenyl)thiophene; 1-[5-(4-Fluorophenyl)-2-thienyl]ethanone; 5-(4-Fluorophenyl)thiophene-2-yl methyl ketone; 4-Fluoro-α-thien-2-ylacetophenone; 886361-46-2; Ethanone, 1-[5-(4-fluorophenyl)-2-thienyl]-; 1-(5-(p-Fluorophenyl)thiophen-2-yl)ethan-1-one
EINECS	Contact for details

Quality Control

Our 1-(5-(4-Fluorophenyl)Thiophen-2-Yl)Ethanone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and residual solvents. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Single Maximum Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.