Description

Methyl 2-Amino-5-(2-Fluorophenyl)-1,3-Thiazole-4-Carboxylate is a high-value, fluorinated thiazole derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where the fluorine atom and thiazole core are key pharmacophores. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries focused on creating new molecules with enhanced biological activity and selectivity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in therapeutic areas targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antimicrobials.
• Agrochemical Research: Used in developing next-generation herbicides, fungicides, and insecticides, where the fluorophenyl-thiazole structure contributes to improved efficacy and environmental profile.
• Chemical Biology Probe Synthesis: Serves as a scaffold for creating molecular probes to study enzyme function and biological pathways in academic and industrial R&D.
• Material Science Precursor: Potential intermediate for synthesizing specialty polymers or organic electronic materials with specific optoelectronic properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.

Basic Information

Product Name	Methyl 2-Amino-5-(2-Fluorophenyl)-1,3-Thiazole-4-Carboxylate
CAS No.	886361-38-2
Molecular Formula	C11H9FN2O2S
Molecular Weight	252.26 g/mol
Synonyms	Methyl 2-amino-5-(2-fluorophenyl)-1,3-thiazole-4-carboxylate; 2-Amino-5-(2-fluorophenyl)-1,3-thiazole-4-carboxylic acid methyl ester; 4-Carbomethoxy-2-amino-5-(2-fluorophenyl)thiazole; 5-(2-Fluorophenyl)-2-amino-1,3-thiazole-4-carboxylic acid methyl ester; 886361-38-2; Methyl 5-(2-fluorophenyl)-2-amino-1,3-thiazole-4-carboxylate
EINECS	Contact for details

Quality Control

Our Methyl 2-Amino-5-(2-Fluorophenyl)-1,3-Thiazole-4-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical and agrochemical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.