Description

Methyl 2-Amino-5-(4-Cyanophenyl)-1,3-Thiazole-4-Carboxylate is a high-value heterocyclic building block and advanced pharmaceutical intermediate. This compound matters for its role in the synthesis of complex molecules, particularly in medicinal chemistry and drug discovery programs. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition or other biological pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging the bioactivity of the thiazole core.
• Material Science: Serves as a monomer or functional component in the creation of advanced polymers, liquid crystals, or organic electronic materials.
• Chemical Biology: Employed as a molecular probe or scaffold for studying protein-ligand interactions and enzyme mechanisms.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and the exploration of new chemical spaces.
• Custom Synthesis: A starting material for the contract manufacturing of proprietary compounds for clients in various life science sectors.

Basic Information

Product Name	Methyl 2-Amino-5-(4-Cyanophenyl)-1,3-Thiazole-4-Carboxylate
CAS No.	886361-36-0
Molecular Formula	C12H9N3O2S
Molecular Weight	259.28 g/mol
Synonyms	Methyl 2-amino-5-(4-cyanophenyl)-1,3-thiazole-4-carboxylate; 2-Amino-5-(4-cyanophenyl)thiazole-4-carboxylic acid methyl ester; 4-Carbomethoxy-2-amino-5-(4-cyanophenyl)thiazole; 5-(4-Cyanophenyl)-2-amino-4-(methoxycarbonyl)thiazole; Methyl 5-(4-cyanophenyl)-2-aminothiazole-4-carboxylate; 886361-36-0; Thiazole-4-carboxylic acid, 2-amino-5-(4-cyanophenyl)-, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 2-Amino-5-(4-Cyanophenyl)-1,3-Thiazole-4-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided for every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.