Description

(3-[3-(Trifluoromethyl)Phenyl]-1,2,4-Oxadiazol-5-Yl)Methanol is a high-value, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where the trifluoromethylphenyl-oxadiazole core imparts desirable biological activity and metabolic stability. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to innovate new molecular entities.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the oxadiazole moiety.
• Material Science Precursor: Serves as a monomer or functional additive in the synthesis of advanced polymers and functional materials with specific optical or electronic properties.
• Ligand Synthesis: Utilized in organometallic chemistry and catalysis for constructing complex chelating ligands.
• Chemical Biology Probe: Acts as a scaffold for developing molecular probes and tools to study biological pathways and protein function.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up campaigns.

Basic Information

Product Name	(3-[3-(Trifluoromethyl)Phenyl]-1,2,4-Oxadiazol-5-Yl)Methanol
CAS No.	886361-32-6
Molecular Formula	C10H7F3N2O2
Molecular Weight	244.17 g/mol
Synonyms	5-(Hydroxymethyl)-3-[3-(trifluoromethyl)phenyl]-1,2,4-oxadiazole; [3-(3-Trifluoromethylphenyl)-1,2,4-oxadiazol-5-yl]methanol; 3-(3-(Trifluoromethyl)phenyl)-1,2,4-oxadiazole-5-methanol; 5-(Hydroxymethyl)-3-(α,α,α-trifluoro-m-tolyl)-1,2,4-oxadiazole; 1,2,4-Oxadiazole-5-methanol, 3-[3-(trifluoromethyl)phenyl]-; (3-(3-(Trifluoromethyl)phenyl)-1,2,4-oxadiazol-5-yl)methanol
EINECS	Contact for details

Quality Control

Our (3-[3-(Trifluoromethyl)Phenyl]-1,2,4-Oxadiazol-5-Yl)Methanol is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect this light-sensitive material from moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.