Description

Ethyl 4-Oxo-2-(2-Toluidino)-4,5-Dihydro-3-Thiophenecarboxylate is a high-value heterocyclic building block featuring a fused thiophene and pyrrolidine-like structure. This compound is essential for advanced organic synthesis, serving as a versatile precursor for the development of novel pharmacologically active molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in medicinal chemistry and drug discovery programs targeting a range of therapeutic areas.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-inflammatory targets.
• Medicinal Chemistry Research: Used as a core scaffold for constructing compound libraries in high-throughput screening (HTS) campaigns to identify new drug candidates.
• Agrochemical Synthesis: Serves as a building block for developing novel herbicides, fungicides, and insecticides with specific modes of action.
• Material Science Precursor: Potential use in the synthesis of organic semiconductors or conductive polymers due to its electron-rich thiophene moiety.
• Academic & Contract Research: Employed in universities and CROs (Contract Research Organizations) for methodological studies in heterocyclic chemistry and catalysis.

Basic Information

Product Name	Ethyl 4-Oxo-2-(2-Toluidino)-4,5-Dihydro-3-Thiophenecarboxylate
CAS No.	886360-76-5
Molecular Formula	C14H16N2O3S
Molecular Weight	292.35 g/mol
Synonyms	Ethyl 2-[(2-methylphenyl)amino]-4-oxo-4,5-dihydro-3-thiophenecarboxylate; 2-(2-Methylanilino)-4-oxo-4,5-dihydrothiophene-3-carboxylic acid ethyl ester; 4,5-Dihydro-4-oxo-2-[(2-methylphenyl)amino]-3-thiophenecarboxylic acid ethyl ester; 886360-76-5; Ethyl 2-(o-toluidino)-4-oxo-4,5-dihydrothiophene-3-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 4-Oxo-2-(2-Toluidino)-4,5-Dihydro-3-Thiophenecarboxylate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the exacting standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.