Description

1-Methyl-3-(trifluoromethyl)-1H-thieno[2,3-c]pyrazole-5-carbohydrazide is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure. This compound is of significant commercial value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular frameworks. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging the biological activity of the thienopyrazole scaffold.
• Chemical Biology & Proteomics: Employed as a specialized reagent or linker in the design of chemical probes for studying enzyme function and protein interactions.
• Material Science: Investigated for its potential application in the synthesis of organic electronic materials due to its fused heterocyclic system.
• Custom Synthesis & Contract Manufacturing: A vital component for CDMOs (Contract Development and Manufacturing Organizations) offering bespoke synthetic routes for client molecules.

Basic Information

Product Name	1-Methyl-3-(trifluoromethyl)-1H-thieno[2,3-c]pyrazole-5-carbohydrazide
CAS No.	886360-63-0
Molecular Formula	C₈H₇F₃N₄OS
Molecular Weight	264.23 g/mol
Synonyms	1-Methyl-3-(trifluoromethyl)-1H-thieno[2,3-c]pyrazole-5-carboxylic acid hydrazide; 1-Methyl-3-trifluoromethyl-1H-thieno[2,3-c]pyrazole-5-carbohydrazide; Thieno[2,3-c]pyrazole-5-carbohydrazide, 1-methyl-3-(trifluoromethyl)-1H-; 886360-63-0; 1H-Thieno[2,3-c]pyrazole-5-carbohydrazide, 1-methyl-3-(trifluoromethyl)-; 5-Hydrazinylcarbonyl-1-methyl-3-trifluoromethyl-1H-thieno[2,3-c]pyrazole
EINECS	Contact for details

Quality Control

Our 1-Methyl-3-(trifluoromethyl)-1H-thieno[2,3-c]pyrazole-5-carbohydrazide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.