Description

[2-(4-Chlorophenyl)-4-Methyl-1,3-Thiazol-5-Yl]Methanamine is a high-purity, functionalized thiazole derivative of significant interest in advanced organic synthesis. This compound matters as a versatile and critical building block for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate a specific chlorophenyl-thiazole scaffold into their target molecules.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antimicrobials.
• Agrochemical Research: Used as a core structural motif in the development of new-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiazole ring.
• Chemical Biology Probe: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and as a building block for creating molecular probes to study biological pathways.
• Material Science Research: Acts as a monomer or functional additive in the development of advanced polymers and organic electronic materials due to its aromatic and heterocyclic structure.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client-specific projects.

Basic Information

Product Name	[2-(4-Chlorophenyl)-4-Methyl-1,3-Thiazol-5-Yl]Methanamine
CAS No.	886360-58-3
Molecular Formula	C11H11ClN2S
Molecular Weight	238.73 g/mol
Synonyms	5-(Aminomethyl)-2-(4-chlorophenyl)-4-methyl-1,3-thiazole; (2-(4-Chlorophenyl)-4-methyl-1,3-thiazol-5-yl)methanamine; 1-(2-(4-Chlorophenyl)-4-methylthiazol-5-yl)methanamine; 4-Methyl-2-(4-chlorophenyl)-5-thiazolemethanamine; 5-(Aminomethyl)-4-methyl-2-(4-chlorophenyl)thiazole; 2-(p-Chlorophenyl)-4-methyl-5-thiazolemethanamine
EINECS	Contact for details

Quality Control

Our [2-(4-Chlorophenyl)-4-Methyl-1,3-Thiazol-5-Yl]Methanamine is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support development and commercial projects requiring material that meets ICH guidelines for impurities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.