Description

4-(3-Bromo-2-Thienyl)-2-Pyrimidinamine is a high-purity brominated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for lead optimization and scale-up activities.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of kinase inhibitors and other small-molecule drug candidates targeting various therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its thienyl-pyrimidine core for bioactivity.
• Material Science: Acts as a building block for organic semiconductors, ligands for catalysis, and other functional organic materials.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for studying biological pathways.
• Academic & Contract Research: Essential for methodological development and discovery chemistry in university and CRO laboratory settings.
• Scale-up & Process Chemistry: Supplied in development quantities to support route scouting, optimization, and pilot-scale production.

Basic Information

Product Name	4-(3-Bromo-2-Thienyl)-2-Pyrimidinamine
CAS No.	886360-54-9
Molecular Formula	C8H6BrN3S
Molecular Weight	256.12 g/mol
Synonyms	4-(3-Bromothiophen-2-yl)pyrimidin-2-amine; 2-Pyrimidinamine, 4-(3-bromo-2-thienyl)-; 4-(3-Bromo-2-thienyl)-2-aminopyrimidine; 4-(3-Bromothien-2-yl)pyrimidin-2-ylamine; 4-(3-Bromo-thiophen-2-yl)-pyrimidin-2-ylamine; CAS 886360-54-9
EINECS	Contact for details

Quality Control

Our 4-(3-Bromo-2-Thienyl)-2-Pyrimidinamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contamination.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.