Description

3-Iodo-6-Nitro-1-(Tetrahydro-2H-Pyran-2-Yl)-1H-Indazole is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceutical agents, particularly in medicinal chemistry programs targeting complex molecular architectures. Pharmaceutical R&D laboratories and fine chemical manufacturers need this high-purity intermediate to facilitate the efficient synthesis of potential drug candidates and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially for targeted therapies.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization stages for constructing indazole-based compound libraries with potential biological activity.
• Agrochemical Development: Employed in the research and synthesis of new generation crop protection agents and herbicides.
• Material Science Precursor: Acts as a precursor for the development of advanced organic electronic materials and ligands for catalytic systems.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations engaged in custom synthesis and process development for clients.
• Academic Research: Utilized in university and institutional labs for methodological studies in heterocyclic and cross-coupling chemistry.

Basic Information

Product Name	3-Iodo-6-Nitro-1-(Tetrahydro-2H-Pyran-2-Yl)-1H-Indazole
CAS No.	886230-74-6
Molecular Formula	C₁₂H₁₂IN₃O₃
Molecular Weight	373.15 g/mol
Synonyms	3-Iodo-6-nitro-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole; 1H-Indazole, 3-iodo-6-nitro-1-(tetrahydro-2H-pyran-2-yl)-; 3-Iodo-6-nitro-1-(tetrahydropyran-2-yl)-1H-indazole; 1-(Oxan-2-yl)-3-iodo-6-nitro-indazole; 886230-74-6; 3-Iodo-6-nitro-1-(2-tetrahydropyranyl)-1H-indazole; THP-Protected 3-Iodo-6-Nitroindazole
EINECS	Contact for details

Quality Control

Our 3-Iodo-6-Nitro-1-(Tetrahydro-2H-Pyran-2-Yl)-1H-Indazole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting compliance in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.