Description

n-(3-Aminopropyl)Maleimide Trifluoroacetate Salt is a high-purity, functionalized maleimide derivative designed for advanced bioconjugation and cross-linking applications. This compound is critical for researchers and manufacturers requiring precise, site-specific modification of biomolecules, such as antibodies and proteins, to create stable conjugates for diagnostics and therapeutics. It is an essential building block for pharmaceutical R&D, biotech companies, and diagnostic kit producers developing targeted drug delivery systems, immunoassays, and ADC (Antibody-Drug Conjugate) platforms.

Application

• Bioconjugation Reagent: Primary use for site-specific labeling and cross-linking of proteins, peptides, and antibodies via thiol-maleimide chemistry.
• ADC (Antibody-Drug Conjugate) Linker Precursor: Serves as a key intermediate in the synthesis of cleavable or non-cleavable linkers for targeted cancer therapies.
• Diagnostic Probe Synthesis: Used to attach fluorescent dyes, enzymes, or other reporter molecules to antibodies for ELISA, flow cytometry, and immunohistochemistry.
• Polymer and Biomaterial Modification: Functionalizes polymers, hydrogels, and surfaces with amine-reactive groups for creating smart biomaterials.
• Peptide and Protein Engineering: Enables the introduction of stable thioether bonds in engineered proteins and peptide-based drugs.
• Research & Development: A valuable tool in academic and industrial R&D for studying protein interactions, cell signaling, and developing novel biotherapeutics.

Basic Information

Product Name	n-(3-Aminopropyl)Maleimide Trifluoroacetate Salt
CAS No.	886209-47-8
Molecular Formula	C10H11F3N2O4
Molecular Weight	280.20 g/mol
Synonyms	3-Maleimidopropan-1-amine trifluoroacetate; N-(3-Aminopropyl)maleimide TFA salt; 1-(3-Aminopropyl)-1H-pyrrole-2,5-dione trifluoroacetate; Maleimidopropylamine TFA salt; APM TFA salt; 3-Maleimidopropylamine trifluoroacetate; N-(3-Aminopropyl)maleimide trifluoroacetic acid salt
EINECS	Contact for details

Quality Control

Our n-(3-Aminopropyl)Maleimide Trifluoroacetate Salt is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity for sensitive research and production applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with cGMP and ISO 9001 standards for critical pharmaceutical and diagnostic use.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry, cool place. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.