Description

6-(4-Methoxyphenyl)-3-Methyl-1,5,6,7-Tetrahydro-4H-Indazol-4-One is a high-purity, advanced pharmaceutical intermediate of significant commercial and research interest. Its value lies in its role as a critical building block for the synthesis of novel bioactive molecules, particularly in medicinal chemistry. This compound is primarily needed by R&D laboratories and production facilities in the pharmaceutical and biotechnology sectors focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities in academic and industrial R&D.
• Biochemical Tool Compound: Used in pharmacological studies to investigate specific biological pathways and enzyme interactions.
• Organic Synthesis Building Block: Employed in multi-step synthetic routes to create more complex heterocyclic compounds due to its reactive indazolone core.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP or non-GMP conditions.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and method development in API (Active Pharmaceutical Ingredient) manufacturing.

Basic Information

Product Name	6-(4-Methoxyphenyl)-3-Methyl-1,5,6,7-Tetrahydro-4H-Indazol-4-One
CAS No.	886158-56-1
Molecular Formula	C15H16N2O2
Molecular Weight	256.30 g/mol
Synonyms	3-Methyl-6-(4-methoxyphenyl)-4,5,6,7-tetrahydro-1H-indazol-4-one; 6-(4-Methoxyphenyl)-3-methyl-4,5,6,7-tetrahydro-1H-indazol-4-one; 4H-Indazol-4-one, 1,5,6,7-tetrahydro-6-(4-methoxyphenyl)-3-methyl-; 3-Methyl-6-(p-methoxyphenyl)-1,5,6,7-tetrahydro-4H-indazol-4-one; 886158-56-1; 6-(4-Methoxyphenyl)-3-methyl-1,5,6,7-tetrahydroindazol-4-one
EINECS	Contact for details

Quality Control

Our 6-(4-Methoxyphenyl)-3-Methyl-1,5,6,7-Tetrahydro-4H-Indazol-4-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request. We support development under various quality paradigms, from research-grade to cGMP standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.