Description

2-Benzyl-Hexahydro-Isoindole-3A,7A-Dicarboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique bicyclic isoindole structure. This compound is of significant commercial value for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily required by research institutions and manufacturers in the pharmaceutical and fine chemical industries for developing novel therapeutic agents, particularly in areas requiring sophisticated chiral and polycyclic frameworks.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of proprietary APIs and new chemical entities (NCEs).
• Organic Synthesis Building Block: Used in constructing complex polycyclic and heterocyclic molecular architectures for medicinal chemistry and material science.
• Asymmetric Catalysis Research: Serves as a precursor or ligand in the development of novel catalytic systems due to its rigid, functionalized structure.
• Peptidomimetic Development: Its dicarboxylic acid and isoindole core make it valuable for designing and synthesizing peptide analogs and enzyme inhibitors.
• Fine Chemical Production: Employed in the custom synthesis of specialty chemicals for agrochemical and high-performance material applications.

Basic Information

Product Name	2-Benzyl-Hexahydro-Isoindole-3A,7A-Dicarboxylic Acid
CAS No.	885956-59-2
Molecular Formula	C17H19NO4
Molecular Weight	301.34 g/mol
Synonyms	2-Benzylhexahydro-1H-isoindole-3a,7a-dicarboxylic acid; 2-Benzyloctahydroisoindole-3a,7a-dicarboxylic Acid; 1H-Isoindole-3a,7a-dicarboxylic acid, 2-(phenylmethyl)octahydro-; BHDI Acid; 2-Benzyl-isoindole-3a,7a-dicarboxylic Acid; 2-Benzyl-perhydro-isoindole-3a,7a-dicarboxylic Acid
EINECS	Contact for details

Quality Control

Our 2-Benzyl-Hexahydro-Isoindole-3A,7A-Dicarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the high standards required for pharmaceutical R&D and cGMP intermediate applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.