Description

Methyl 3,5-Diiodo-1H-Indole-2-Carboxylate is a high-value, multi-functional indole derivative serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in providing a versatile, halogenated scaffold for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity building blocks for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting neurological disorders, oncology, and anti-inflammatory pathways.
• Medicinal Chemistry Research: Used extensively in structure-activity relationship (SAR) studies and lead optimization due to its modifiable indole core and halogen substituents.
• Agrochemical Synthesis: Serves as a building block for developing new generation herbicides, fungicides, and plant growth regulators.
• Material Science: Potential monomer or precursor for specialty polymers, organic semiconductors, and liquid crystals.
• Chemical Biology: Utilized in the development of molecular probes and enzyme inhibitors for biochemical research.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and novel compound library synthesis.

Basic Information

Product Name	Methyl 3,5-Diiodo-1H-Indole-2-Carboxylate
CAS No.	885949-47-3
Molecular Formula	C10H7I2NO2
Molecular Weight	426.98 g/mol
Synonyms	Methyl 3,5-diiodoindole-2-carboxylate; 1H-Indole-2-carboxylic acid, 3,5-diiodo-, methyl ester; 3,5-Diiodo-1H-indole-2-carboxylic acid methyl ester; 2-Carbomethoxy-3,5-diiodoindole; Methyl 3,5-diiodo-1H-indole-2-carboxylate; 885949-47-3
EINECS	Contact for details

Quality Control

Every batch of Methyl 3,5-Diiodo-1H-Indole-2-Carboxylate is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from HPLC, NMR, and mass spectrometry. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring reliable supply and traceability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.