Description

1-Acetyl-4-Bromo-1H-Indazole is a high-purity, functionalized indazole derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of novel pharmaceuticals and agrochemicals, enabling precise molecular modifications. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating complex, biologically active molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging the indazole core's bioactivity.
• Material Science: Serves as a monomer or functional additive in the creation of specialty polymers and advanced organic electronic materials.
• Chemical Biology: Employed as a probe or labeling reagent in biochemical assays and proteomics research due to its reactive bromo and acetyl groups.
• Academic & Contract Research: Utilized in university and CRO laboratories for method development and exploring new synthetic pathways in heterocyclic chemistry.

Basic Information

Product Name	1-Acetyl-4-Bromo-1H-Indazole
CAS No.	885698-70-4
Molecular Formula	C9H7BrN2O
Molecular Weight	239.07 g/mol
Synonyms	4-Bromo-1-acetyl-1H-indazole; 1H-Indazole, 4-bromo-1-acetyl-; 4-Bromo-1H-indazole-1-acetic acid (tautomer); 4-Bromoindazole-1-acetyl; 1-Acetyl-4-bromoindazole; 4-Bromo-1-(acetyl)indazole; 885698-70-4; 4-Bromo-1H-indazole, 1-acetyl derivative
EINECS	Contact for details

Quality Control

Our 1-Acetyl-4-Bromo-1H-Indazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.