Description

5-Methoxy-3-[(Pyrrolidin-1-Yl)Methyl]-1H-Indole is a versatile indole derivative that serves as a critical building block in advanced organic synthesis. Its unique molecular scaffold, featuring a methoxy-substituted indole core linked to a pyrrolidine moiety, makes it a valuable intermediate for pharmaceutical research and development. This compound is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries for creating novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates targeting central nervous system (CNS) disorders, serotonin receptors, and other neurological pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Chemical Biology Probe Development: Serves as a starting material for creating tool compounds to study biological mechanisms and protein interactions.
• Process Chemistry & Scale-up: Employed in route development and optimization for the commercial manufacturing of active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in university and institutional laboratories for methodological development in heterocyclic and indole chemistry.

Basic Information

Item	Details
Product Name	5-Methoxy-3-[(Pyrrolidin-1-Yl)Methyl]-1H-Indole
CAS No.	885526-18-1
Molecular Formula	C15H20N2O
Molecular Weight	244.33 g/mol
Synonyms	1H-Indole, 5-methoxy-3-[(1-pyrrolidinyl)methyl]-; 3-(Pyrrolidin-1-ylmethyl)-5-methoxy-1H-indole; 5-Methoxy-3-(pyrrolidin-1-ylmethyl)indole; 5-Methoxy-3-pyrrolidin-1-ylmethyl-1H-indole; 885526-18-1
EINECS	Contact for details

Quality Control

Our 5-Methoxy-3-[(Pyrrolidin-1-Yl)Methyl]-1H-Indole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, confirming compliance with customer specifications and industry best practices for research-grade chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.