Description

1-Isopropyl-5-Methoxy-1H-Indole-3-Carboxylic Acid is a high-purity, functionalized indole derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of novel pharmaceuticals and bioactive molecules, particularly those targeting neurological and oncological pathways. It is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality intermediates for complex multi-step syntheses.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those with indole-based scaffolds for central nervous system (CNS) and anticancer applications.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and plant growth regulators that leverage the indole moiety's biological activity.
• Fine Chemical Synthesis: Serves as a versatile building block for creating complex molecules used in material science, dyes, and specialty polymers.
• Academic & R&D Laboratories: Employed in medicinal chemistry research for structure-activity relationship (SAR) studies and the discovery of new bioactive compounds.
• Process Chemistry: Utilized in scaling up synthetic routes for active pharmaceutical ingredients (APIs) where the isopropyl and methoxy substituents are crucial for desired pharmacokinetic properties.

Basic Information

Product Name	1-Isopropyl-5-Methoxy-1H-Indole-3-Carboxylic Acid
CAS No.	885525-18-8
Molecular Formula	C14H17NO3
Molecular Weight	247.29 g/mol
Synonyms	5-Methoxy-1-(propan-2-yl)-1H-indole-3-carboxylic acid; 1H-Indole-3-carboxylic acid, 5-methoxy-1-(1-methylethyl)-; 1-Isopropyl-5-methoxyindole-3-carboxylic acid; 1-(Isopropyl)-5-methoxy-1H-indole-3-carboxylic acid; 885525-18-8; 1-Propan-2-yl-5-methoxy-indole-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-Isopropyl-5-Methoxy-1H-Indole-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and production. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong acids.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.