Description

6-Bromo-3-Chloro-4-(1H)Indazole Methyl Carboxylate is a high-purity, advanced pharmaceutical intermediate with a defined heterocyclic structure. This compound is critical for medicinal chemistry research and the synthesis of novel active pharmaceutical ingredients (APIs), particularly in oncology and kinase inhibitor development. It is primarily utilized by R&D laboratories, custom synthesis providers, and pharmaceutical manufacturers engaged in the development of targeted therapies.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, especially kinase inhibitors and other targeted cancer therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel therapeutic targets.
• Custom Synthesis & Contract Manufacturing: Serves as a critical starting material or intermediate for custom API synthesis and process development.
• Biochemical Research: Employed as a probe or reference standard in biochemical assays to study enzyme inhibition and cellular pathways.
• Academic Research: Utilized in university and institutional labs for the development of new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	6-Bromo-3-Chloro-4-(1H)Indazole Methyl Carboxylate
CAS No.	885523-85-3
Molecular Formula	C9H6BrClN2O2
Molecular Weight	289.51 g/mol
Synonyms	Methyl 6-Bromo-3-chloro-1H-indazole-4-carboxylate; 6-Bromo-3-chloro-1H-indazole-4-carboxylic acid methyl ester; 1H-Indazole-4-carboxylic acid, 6-bromo-3-chloro-, methyl ester; 885523-85-3; Methyl 6-bromo-3-chloro-4-indazolecarboxylate; 6-Bromo-3-chloro-4-(1H-indazole)methyl carboxylate
EINECS	Contact for details

Quality Control

Our 6-Bromo-3-Chloro-4-(1H)Indazole Methyl Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) for every shipment, supporting your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.