Description

4-Bromo-3-Iodo-6-Indazolecarboxylic Acid Methyl Ester is a high-purity, multi-halogenated indazole derivative that serves as a critical advanced intermediate in modern synthetic chemistry. Its unique halogen substitution pattern makes it a valuable scaffold for constructing complex molecules with tailored properties. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of targeted small molecule drugs, particularly kinase inhibitors and other therapeutic agents.
• Agrochemical Research: Used in the development of new generation herbicides and pesticides due to its halogenated heterocyclic structure.
• Material Science: Serves as a precursor for organic electronic materials, such as ligands for OLEDs or charge-transport materials.
• Chemical Biology: Employed as a probe or linker in bioconjugation chemistry and proteolysis-targeting chimera (PROTAC) development.
• Academic & Contract Research: Essential for methodological studies in cross-coupling reactions and heterocyclic chemistry.

Basic Information

Product Name	4-Bromo-3-Iodo-6-Indazolecarboxylic Acid Methyl Ester
CAS No.	885523-66-0
Molecular Formula	C9H6BrIN2O2
Molecular Weight	380.97 g/mol
Synonyms	Methyl 4-Bromo-3-Iodo-1H-indazole-6-carboxylate; 1H-Indazole-6-carboxylic acid, 4-bromo-3-iodo-, methyl ester; 4-Bromo-3-iodo-1H-indazole-6-carboxylic acid methyl ester; Methyl 4-bromo-3-iodo-1H-indazole-6-carboxylate; 885523-66-0; 4-Br-3-I-6-indazole-COOMe
EINECS	Contact for details

Quality Control

Our 4-Bromo-3-Iodo-6-Indazolecarboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for research-grade chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to minimize exposure to moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.