Description

4-Chloro-3-Iodo-6-Indazolecarboxylic Acid is a high-purity, multi-halogenated heterocyclic building block of significant interest in advanced organic synthesis. Its unique molecular scaffold, featuring both chloro and iodo substituents, makes it a versatile intermediate for constructing complex pharmacophores and functional materials. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for targeted molecular discovery and optimization.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel kinase inhibitors, anticancer agents, and other biologically active small molecules.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators due to its halogenated indazole core.
• Material Science: Acts as a building block for organic semiconductors, liquid crystals, and metal-organic frameworks (MOFs) requiring specific halogen interactions.
• Chemical Biology: Employed in the design of molecular probes, tags, and covalent inhibitors for target identification and validation studies.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects requiring regioselectively halogenated indazole derivatives.

Basic Information

Item	Details
Product Name	4-Chloro-3-Iodo-6-Indazolecarboxylic Acid
CAS No.	885523-34-2
Molecular Formula	C8H4ClIN2O2
Molecular Weight	322.49 g/mol
Synonyms	6-Indazolecarboxylic acid, 4-chloro-3-iodo-; 4-Chloro-3-iodo-1H-indazole-6-carboxylic acid; 4-Chloro-3-iodoindazole-6-carboxylic acid; CAS 885523-34-2
EINECS	Contact for details

Quality Control

Our 4-Chloro-3-Iodo-6-Indazolecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC for purity, NMR and MS for structural confirmation, and elemental analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.