Description

3-Cyano-6-Nitro-4-(1H)Indazole Carboxylic Acid Methyl Ester is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the research and development of novel therapeutic agents, particularly in oncology and targeted drug discovery. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers requiring a reliable and consistent supply of specialized building blocks.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel small-molecule drug candidates, particularly kinase inhibitors.
• Oncology Research: Used in the development of targeted cancer therapies due to its indazole-based scaffold.
• Chemical Biology: Serves as a probe or precursor for studying enzyme function and biological pathways.
• Agrochemical Research: Potential intermediate for developing new active ingredients with specific biological activity.
• Material Science: Investigated as a precursor for specialty polymers or organic electronic materials.
• Academic & Institutional Research: Used in universities and research institutes for synthetic methodology and medicinal chemistry projects.

Basic Information

Product Name	3-Cyano-6-Nitro-4-(1H)Indazole Carboxylic Acid Methyl Ester
CAS No.	885523-29-5
Molecular Formula	C11H6N4O4
Molecular Weight	258.19 g/mol
Synonyms	Methyl 3-cyano-6-nitro-1H-indazole-4-carboxylate; 6-Nitro-3-cyano-1H-indazole-4-carboxylic acid methyl ester; 4-(1H)-Indazolecarboxylic acid, 3-cyano-6-nitro-, methyl ester; 885523-29-5; Methyl 6-nitro-3-cyano-1H-indazole-4-carboxylate
EINECS	Contact for details

Quality Control

Every batch of 3-Cyano-6-Nitro-4-(1H)Indazole Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for each shipment, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.