Description

4-Chloro-3-Iodo-6-Indazolecarboxylic Acid Methyl Ester is a high-value, multi-halogenated indazole derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique halogen substitution pattern makes it a versatile building block for constructing complex heterocyclic scaffolds with potential biological activity. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and for use in medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis due to its reactive halogen sites.
• Agrochemical Development: Building block for creating new active ingredients in crop protection and pest management products.
• Chemical Biology Probes: Utilized in the development of molecular probes and tags for studying biological pathways and protein interactions.
• Material Science Research: Potential monomer or precursor for specialty polymers and advanced organic materials with specific electronic properties.

Basic Information

Product Name	4-Chloro-3-Iodo-6-Indazolecarboxylic Acid Methyl Ester
CAS No.	885523-07-9
Molecular Formula	C9H6ClIN2O2
Molecular Weight	336.51 g/mol
Synonyms	Methyl 4-Chloro-3-iodo-1H-indazole-6-carboxylate; 4-Chloro-3-iodo-1H-indazole-6-carboxylic acid methyl ester; 6-Indazolecarboxylic acid, 4-chloro-3-iodo-, methyl ester; 1H-Indazole-6-carboxylic acid, 4-chloro-3-iodo-, methyl ester; 885523-07-9; Methyl 4-chloro-3-iodoindazole-6-carboxylate; 4-Chloro-3-iodo-6-methoxycarbonylindazole
EINECS	Contact for details

Quality Control

Our 4-Chloro-3-Iodo-6-Indazolecarboxylic Acid Methyl Ester is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.