Description

3-Bromo-6-Chloro-4-Indazole Carboxylic Acid Methyl Ester is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in its versatile indazole scaffold, which serves as a critical intermediate for constructing complex molecules with targeted biological activity. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, leveraging its halogenated indazole structure.
• Chemical Biology & Proteomics: Serves as a versatile scaffold for designing molecular probes and activity-based protein profiling (ABPP) reagents.
• Material Science Research: Investigated as a precursor for specialty polymers and advanced organic electronic materials due to its rigid, aromatic structure.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and libraries.
• Academic Research: Utilized in university and institutional laboratories for methodological development in heterocyclic and medicinal chemistry.

Basic Information

Product Name	3-Bromo-6-Chloro-4-Indazole Carboxylic Acid Methyl Ester
CAS No.	885522-96-3
Molecular Formula	C9H6BrClN2O2
Molecular Weight	289.51 g/mol
Synonyms	Methyl 3-bromo-6-chloro-1H-indazole-4-carboxylate; 3-Bromo-6-chloro-1H-indazole-4-carboxylic acid methyl ester; 6-Chloro-3-bromo-1H-indazole-4-carboxylic acid methyl ester; 885522-96-3; 3-Bromo-6-chloroindazole-4-carboxylic acid methyl ester; Methyl 3-bromo-6-chloro-4-indazolecarboxylate; 4-Indazolecarboxylic acid, 3-bromo-6-chloro-, methyl ester
EINECS	Contact for details

Quality Control

Our 3-Bromo-6-Chloro-4-Indazole Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.