Description

6-Amino-4-Fluoro-3-(1H)Indazole Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with significant synthetic utility. Its core value lies in its role as a key building block for constructing complex heterocyclic molecules, particularly in medicinal chemistry. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors developing novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug candidates, especially kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for new chemical entities.
• Agrochemical Development: Serves as a building block for creating novel herbicides and pesticides with specific modes of action.
• Organic Synthesis: Employed in academic and industrial R&D for constructing indazole-based heterocyclic frameworks.
• Bioconjugation: The carboxylic acid and amino functional groups allow for derivatization and conjugation to biomolecules or other chemical entities.

Basic Information

Product Name	6-Amino-4-Fluoro-3-(1H)Indazole Carboxylic Acid
CAS No.	885522-68-9
Molecular Formula	C8H6FN3O2
Molecular Weight	195.15 g/mol
Synonyms	4-Fluoro-6-amino-1H-indazole-3-carboxylic acid; 6-Amino-4-fluoro-1H-indazole-3-carboxylic acid; 3-Carboxy-6-amino-4-fluoroindazole; 885522-68-9; 4-Fluoro-6-aminoindazole-3-carboxylic acid; 6-Amino-4-fluoroindazole-3-carboxylic acid; 1H-Indazole-3-carboxylic acid, 6-amino-4-fluoro-
EINECS	Contact for details

Quality Control

Our 6-Amino-4-Fluoro-3-(1H)Indazole Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical-grade intermediates. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 98.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity	≤ 0.5%
Total Impurities	≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.