Description

6-Chloro-3-Hydroxy-4-(1H)Indazole Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its indazole carboxylic acid core structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs) and serves as a versatile building block in medicinal chemistry research. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of targeted therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates targeting various therapeutic areas.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Active Pharmaceutical Ingredient (API) Development: Employed in the research and development of new APIs, particularly those with indazole-based structures.
• Biochemical Research: Serves as a tool compound for studying enzyme inhibition and other biological pathways.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	6-Chloro-3-Hydroxy-4-(1H)Indazole Carboxylic Acid
CAS No.	885522-15-6
Molecular Formula	C8H5ClN2O3
Molecular Weight	212.59 g/mol
Synonyms	6-Chloro-3-hydroxy-1H-indazole-4-carboxylic acid; 4-Carboxy-6-chloro-1H-indazol-3-ol; 6-Chloro-3-hydroxy-4-carboxyindazole; 1H-Indazole-4-carboxylic acid, 6-chloro-3-hydroxy-; 885522-15-6; 6-Chloro-3-hydroxyindazole-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 6-Chloro-3-Hydroxy-4-(1H)Indazole Carboxylic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.